The DNA methylation, in human cells regulates tumor growth
and it also indicates the breast cancer susceptibility. In a research they pinpointed the genes that are involved invariations that occur in methylationof the breast cancer epigenome. The DNA methylation(CG sites)sequences from
7-normal individuals and 8-breast cancer patients were compared by using
Statistical software package R and by Upperone-tailed chi-square tests.
Consensus Path Database is used to map selected CG sites to study the
biological relations between healthy individuals with patients affected by
tumour. Based on the data collected from PubMed and Gene Card, 26 potential
biomarker genes were discovered. All these data helps in the development of
novel treatments for breast cancers.
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