Cellular functions such as the
maintenance of homoeostasis are regulated by shear forces sensed by endothelial
cells. The endothelial cells sense local changes by absorbing the stress and produces signals that either transduce chemical responses or transmit the same to regulate the cellular activity. Certain parts of our body are prone to
plaque phenotype and they rupture due to plaque accumulation. The blood cells
that are smaller in size under the normal conditions grow in size to block the
blood flow through the arteries. Severe stenosis and the local particle
concentration leads to high cardio vascular inflammation.
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